Regenerative Medicine

B3 Spine, Sport and Wellness Your Leader in Stem Cell and PRP Therapies Life is a Sport— We will get you back in the game!
Regenerative Medicine
Regenerative medicine is the process of replacing, renewing or engineering human cells, tissues, organs, proteins, etc for the purposes of restoring function and homeostasis in the body. It uses any means to heal otherwise nonfunctional cells, tissues and organs. One of the key components of regenerative medicine is the use of cell replacement strategies which many times requires stem cells.

What are Stem Cells?
These are unspecialized cells in our bodies that have the capacity to change into any healthy cell in our body. Meaning they can change into skin, bones, heart and muscle cells to name a few. They have the ability to replicate substantially as compared to normal somatic cells such as skin. Stem cells are located throughout our body in almost every organ and tissue such as bone marrow, fat, teeth, muscles, etc. However, as other cells in our body, stem cells also age as we do. That is why B3 uses stem cells from umbilical cord tissue which are young and healthy.

B3’s stem cells are derived from umbilical cord tissue, which is the safest and least-invasive method of extraction available.

Our Regenerative Medicine Product
B3 Stem Cells Come From Umbilical Cord Tissue Donations and Bone Marrow Aspiration.

B3’s main stem cell regenerative medicine product is derived from Umbilical Cord Tissue Donations. Our product contains mesenchymal stem cells (MSCs) and is rich in growth factors from umbilical cord tissue. We obtain these tissues under informed consents and strict ethical protocols. These tissues are from safe, reliable hospital sources via a non-invasive, simple, and painless procedure.

Here’s how it works:
Participating hospitals invite screened mothers expecting normal, healthy births to donate the resulting umbilical cord tissues. These otherwise discarded tissues are an excellent source of high-quality stem cells and growth factors which may be used in regenerative medicine. At the time of birth, a specialized nurse enters the delivery room to carry out the extraction procedures. The umbilical cord tissue and blood is extracted and taken to our lab which follows cGMP and GTP procedures. From here our regenerative medicine product is made.
All the tissues obtained are screened under AATB standards in order to assure the highest quality product. Our regenerative medicine product is sold in standardized concentrations making it easy for you the practitioner to deliver a dependable product.

Our cells are strictly screened, high-quality, and provided in standardized concentrations. Using stem cells gives patients a wide range of benefits via therapies that can be conducted in under half an hour.

In addition we may use stem cells derived from
Your own Bone Marrow- Some people like to know that it is there own tissue that they are receiving.
Adult stem cells can be extracted from bone marrow by aspiration, typically from the superior iliac crest or the sternum. This process may be painful, though much research has been done to reduce any pain incurred by patients during extraction. At B3 bone marrow aspiration is done under anesthesia to reduce the possibility of the pain from the extraction technique.

Other Stem Cell Sources Include:
Embryonic tissue: Most embryonic stem cells (human embryonic stem cells, or hESCs) are derived from embryos donated from fertility clinics that perform in vitro fertilization, or IVF.
Adipose tissue: Adipose-derived stem cells come from a patient’s fat tissue, which is surgically extracted via liposuction under general anesthesia.

B3’s umbilical-cord-derived regenerative medicine product contains MSCs that are both safe and non-invasive for donors, as well as a reliable source for our patients.

At B3 Spine Sport and Wellness our umbilical-cord derived stem cells also come from the youngest postnatal cells and do not rely upon embryonic tissue (the use of which brings up ethical issue for some of our patients). https://www.ncbi.nlm.nih.gov/pubmed/24552279

In July 2005, Cardinal William H. Keeler, then chairman of the Committee for Pro-Life Activities, U.S. Conference of Catholic Bishops, and a former bishop of Harrisburg, wrote in a USCCB newsletter that “umbilical cord blood stem cells have successfully treated thousands of patients with dozens of diseases.

“They also exhibit properties once associated chiefly with embryonic stem cells: They grow rapidly in culture, producing enough cells to be clinically useful in both children and adults; they can treat patients who are not an exact genetic match, without being rejected as foreign tissue; and they seem able to produce a wide array of different cell types.

WHICH CONDITIONS BENEFIT MOST FROM STEM CELLS?
Cartilage and joint function improvement
In the area of joint injury and degeneration, mesenchymal (MSC) stem cells are being used to improve the function of joints. There are greater than 20 clinical studies or case studies in the peer reviewed scientific literature all demonstrating that stem cells may regenerate tissue, improve function, reduce pain and improve the quality of life for those suffering from orthopedic problems.
Regenerative therapies utilize the anti-inflammatory properties of mesenchymal stem cells to alleviate inflammation-related osteoarthritis (OA) pain. In a 2011 study, for example, patients with severe OA were injected with mesenchymal stem cells and found they were able to walk longer without pain and climb a greater number of stairs after treatment. A follow-up study five years later showed that improvements had decreased, but that the knee that had received stem cell treatment was still better than at baseline. There are many other studies similar to this all supporting the notion that stem cells may be beneficial in treating arthritic conditions.

WHAT IS PRP (PLATELET RICH PLASMA)?
Platelet Rich Plasma therapy (PRP) is a ground breaking non-operative treatment option that relieves pain by naturally promoting long lasting healing of musculoskeletal conditions. PRP has most recently been featured in the news with the rising popularity of the treatment among professional and elite athletes. Many have attributed PRP injections, with enabling them to return back to regular activities and competition with minimal to no pain at all. This rapidly emerging technique shows very promising potential for many conditions such as arthritis, tendonitis, and ligament sprains and tears.
PRP therapy presents patients with a long lasting, permanent solution through the body’s natural healing process. PRP is not something that wears off over time as with a traditional pain injection.

Platelet rich plasma, commonly referred to as “PRP”, is human blood that is spun down and separated producing a concentration of platelets above normal values. Platelets are the clotting cells of our blood, but they also have great potential in enhancing healing of muscle, tendon, and ligaments. Studies suggest that growth factors released by platelets recruit reparative cells, may augment tissue repair, and accelerate soft tissue healing.

WHICH CONDITIONS BENEFIT MOST FROM PRP?
PRP treatment works most effectively for chronic ligament and tendon sprains/strains that have failed other conservative treatment, including but not limited to:

  • Lumbar spine disc pain
  • Rotator cuff injuries, including partial-thickness
  • Shoulder pain and instability
  • Tennis and golfer’s elbow
  • Hamstring and hip strains
  • Knee sprains and instability
  • Patellofemoral syndrome and patellar tendonitis
  • Ankle sprains
  • Achilles tendonitis & plantar fasciitis
  • Knee, hip, and other joint osteoarthritis
  • Nerve entrapment syndromes, such as Carpal Tunnel Syndrome
  • Sacroiliac (SI) joint dysfunction and pain
  • Lumbar and cervical facet dysfunction and pain

Additionally, PRP can be effective for many cases of osteoarthritis by stimulating healing of cartilage and reducing pain and disability. This includes:

  • Knee arthritis
  • Hip joint arthritis
  • Shoulder arthritis
  • Ankle arthritis

WILL PRP TREATMENT HELP ME AVOID SURGERY?
With any treatment option the outcome and sustained results are highly dependent on the extent of the injury. For example in the case of mild arthritis, PRP could potentially prevent the development of further degeneration. However, in advanced arthritic degeneration the goal of the treatment is to minimize pain and improve function. PRP (potentially if used in tandem with the use of stem cells) could avoid surgery such as joint replacements and potentially spinal fusion.

Stem cells and cell based therapies have shown tremendous promise; yet controlled studies are still needed in order to confirm its efficacy. Professional judgment and expertise is needed in using these therapies for any therapeutic use, and we urge anyone embarking on the use of stem cell therapies or any regenerative medicine product to consult the national health data bases to evaluate current information from clinical trials. The FDA websites on human tissue should also be consulted to get its current evaluation of any regenerative therapy.

Stem cells, and PRP like other medical products that are intended to treat, cure or prevent disease, generally require FDA approval before they can be marketed. FDA has not approved any stem cell-based or regenerative medicine products for use, other than cord blood-derived hematopoietic progenitor cells (blood forming stem cells) for certain indications.
http://www.fda.gov/AboutFDA/Transparency/ Basics/ucm194655.htm

Please call B3 Spine, Sport & Wellness at 844 400 2246 to schedule your Free consult .